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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63461fa593d26e4981c74b7e241d5214f954a5805b30d6d7aef72c9212d59a01' 
  AND token = '9d8buHhwBcRcQ2Y/mYpR/MOOyusVSRUQ4hqKNdqmL90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}