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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49e6f72fe4782f0b751859c7be80adb89ab1e1e3bfae197f69dc02bd2b7d31f' 
  AND token = '1n0abpLqJuwy7AXmfH/RQ4U5oJTWSGaaVzxf0Luw2+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}