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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e69a17a09ef1354421dcbebeb13211799c161222b2b355e9f7484ed7c26f3c89' 
  AND token = 'FCaZfLDOEZIkr8vzxEET96aUKMkeGP6/9mv3qydm/OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}