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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dcc04a00eb4cffeb76625ef48ec1d845e8256418ee04b0d73327030267ca036' 
  AND token = '6Ye+5XwvdJLWBeAgUyal6LzVUXO4pz5/gxwvcWb/IWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}