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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46cc7cced2c01e02d315e4fc314aec6050a21ccdf6672a87bb7f052114d1cc5' 
  AND token = 'UJfP0kYjDbv/BqvH3mkpsrbk8vE1i9i5rOknWMG4q/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}