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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdfa54dda2244dc89ee833ce8e3fc4d6c96e3521748f97fa100d150d7188cbf1' 
  AND token = 'LF+gcm+zgz7tCMr8H8hezrhITuxBt4KFLe7PXb6clc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}