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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e8f98827a6d8f59dfcfa3841d39863384a724dc951d67e96c904cdc88f5662' 
  AND token = '1rA0FmIBx38nvLEHZgUcS+1/qk18eATd/t46svIESBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}