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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fedaa4136a33819c6e94982fed2c7ce05fca42cd8fc35b24356c128b82afcc1' 
  AND token = 'XPUl+NFpa4AiRLiS1dVhYd/6vW7DRL6/Ddv6JDzv+8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}