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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5056922b678aa16328e7d16adacafa0685c38d7cedb7b92785406f1f61f346' 
  AND token = 'AQcrrmAS2YuMwGY1FFl9hbMriHaFCROcrUif1rdruoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}