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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d4dea798a81dcd2bb31eed794cc2a227315c5892d6d870a3260aec83d3d9129' 
  AND token = 't/Z5XCzw4bjXza6JrxofGc4fsNpFqWhObDG/3xzwIjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}