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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da0eef98d427ba4933a1561fb926c2b89624c7027f28c8b5b9889d022d25316d' 
  AND token = '4/57+S42c7psVolDb6/RUyjbqOx1X2wGQNjXBWg421U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}