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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea68ff2a54f362b152cb8857eaf39489eb006742cc9095d0c3eb2f1076e17ac6' 
  AND token = 'T6Kt6ub/muwBJMFyzqiznopr4N0y0lcNrIQVRsZRbI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}