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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6294ce7d4c26c1a64af30fa0b574871e3c9c06f76e823a98e7a717b01ad74729' 
  AND token = 'tsGhjwA180XDbWJTyLUPVr8C8HWppWGmquN4oXuConM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}