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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50a0f2ef000b09c7963b429ed9161c855ef664d67252539aebf9260149fed87' 
  AND token = 'bEiQ0UEU+Ot95P4NzrhAsUci8pc1cy8lhzCTe+hnOuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}