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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d0ed8b262ee4989ba9fb4a530dcc7a057589137c2ea0a1d2f9655f1894174a' 
  AND token = '9l22Y1EHW92hh4JIgxMnsyAbZBE+65VCRrKyMN8T8U0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}