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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea1948a2debada989a2c8089e30bcaff202c1468a1e813ae42889a53814beb1' 
  AND token = '+/5L2FRbT7uld18eYq8ZrWrEVI6AtETCCbddb9eAkm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}