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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3d651463adc7dda07e6ecb114d9c3511f9a01f6bfaa2ba4bd585f45179c3905' 
  AND token = 'C2yn8KZaSaSi4z+g4ci5nL5qxTZ8oaNbY8RANKK2oDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}