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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45ddf9f94b31b0c88d7a6faf645e299c6b3ca0ad70a358d68ea682abbf8bc57' 
  AND token = 'iLIpC2I5SVAN6QdVsaxTobPjEEbsldV1S9k/5MDRgSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}