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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc5ae6a4dc22321288d55fa405c32ba8e8cd409011a06aae173f5a2ef727401' 
  AND token = 'pq9gSOUUEXVcvlUlONb4S01jiuDKEsqyh3dPkIDdBgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}