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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddd166d4d1b2ce7fbe7fe009939899f2073dc10cecd1dfff94a303936e9e7a70' 
  AND token = '7sADQVYbAZq4ZCmWjz8SqzMM4ADo/wIF01aPHfFp+P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}