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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b452121c8b26691374baa6fad19304a0929279e213c71a2fd84081e19e300936' 
  AND token = 'p0uVr+sXPjU6MyOGPp4Qe4nVqqClPS/ybffdMvd5RdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}