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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24fd07dadd89dd5d368572a973ee88d1458b5839373c83be8367a532932ad5c4' 
  AND token = 'lYjV6Aqw0CAxuzxK1+vWIOSu9mB4RUzzh0x53EO6Yic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}