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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff9be085dfd704e321a0c019e48956d767e2758aba50ba598f48271463d02d17' 
  AND token = '5SVRdUaxOa7l4s1+jr0mVNhDfphOV3etsE3Eu2ne4rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}