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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a6a92647eda29610f92325ac9add1996b465344de163f3614a0aaf75df5194' 
  AND token = 'UsxZrShNYkgx0+4aW9J9Qoe+YGjWWUnpkLfuhTst8nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}