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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f6188171a641fa5e7139aa674b37b349f1c8a17512a554eb1caff8374a13dd' 
  AND token = '+0NbS1mYG+X0feWHy0aQGMu6mPibB4qEJqKwgTRkjak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}