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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c281d984f0c7f3568961f32c5951470ceae8667740e668833878dde82eab2b4' 
  AND token = 'FkJpLWwRZHN8qb6Rj6xFPY3Jw+R12cI3vCmqa9FBOEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}