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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a57e48cc4c0d1c80c290b42a6e597b0692cd8b3df03dbe2c6b2d439070654d' 
  AND token = 'DAyh7ZMHUjWiabRhdG4TbM/rnc67OpPKYy351Z7SoOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}