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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '834c2cdfa365921b2dae7a993ac91baafff45285e8e9a133638cc83f8537e2c3' 
  AND token = 'r26++X8zz5BxKLvIcPPmkYLmFSUuUmYY8eaOP+bMnMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}