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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2aafc241097d053df91afd9c03e50e7cb4016e09c5da73a30d91546ea8add5b' 
  AND token = 'qlVYHr36brErma774zB0SVFs+1HQNw90H1E1UUcQe3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}