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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f9db6ec89708bc410cc5172f5f9cb42055ec90f09bea14fb682d96c518b8b0f' 
  AND token = '2hTb+GBCmGVRlKMH/ytnpa9OUf3Ra8QiWigKq3rqjBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}