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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcf1a5ab8d67985b026f2d515b9e9e6db6ee220024b9105901084807ddcc17a5' 
  AND token = 'X17xM49Qc2LhxWMw/YibD7d7oz+KJgrc5IaRRcCvQbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}