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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a82a6bfc09810273e2249970091aa1004ce174a80b5f88a2e491dcdab1cbed97' 
  AND token = 'vSEqFEaQmDPtp1cyz5uhn5OkLNjHh/Ax1Ry82733TTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}