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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effe22daf434f372f4d19e91ef74284a54933ecb309414d1d55356b013a73c35' 
  AND token = 'O2kWXxpOmr8YqPxVKz52FIE2tvEXfL9wdd21rs+3AzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}