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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10b1d8090158f9bd538ba4f86d44f4ff460314e569f894b825888bbff998b86' 
  AND token = '073TMnp2o9itE1mNC5nIF8r8xgSO3dkef+OGlXWqn3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}