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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8c04143302629059a3a2023b98da0c312f4d09ee9d9005c6a5a2a80c40c18a' 
  AND token = 'DYUsZAK+olfO4U+lGhAD1Z9vUW60eF5qOYUChKr1/50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}