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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b169e619e14afae011923e3bba4d7a98a02d49072e5053a79721aefa4b384a05' 
  AND token = '8kdpAYlwOQikbnLCuMPVBHb1lEcbUw45Xb/xkYExm8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}