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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0722aedcf3f4ba69aa6cd4ddf8b329642372724e65a06a72f737f99fdd98a9' 
  AND token = 'yJ4SQTR3z7mA3IHoPWpne0/nUoiEvskVbr5T1fTYoiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}