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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4a2dc81fcce81d170fb208adb0776435afdcdf45581d2b1a75902ade247bb7' 
  AND token = '82WTisQUAvYBuvynTAhE/icQL1x8GJxtKO/P4ih6uf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}