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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a380bc42f5a5eb8dbf341be8e44dbfce4e532f2e819f0e69131b1238b661bbf6' 
  AND token = 'LZHXr3R5Yk8q0emOoWcsTvE1xnEU9vPICucfLadbd1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}