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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fd6061d84cb64d284ee22200f4b5369854040deb850ed8603d147382465f854' 
  AND token = 'b/4dAHDlJZPEaugWlTvooqUS+nJ1RZk78AgStXCTfqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}