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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a925f29d647ee917714da899878cc42e5e0f2ed8552b443cd11edb493f1350d1' 
  AND token = 'nKIyelOjikdPHxIiPA+tbTaXxPraQ+SywTAFSZf4+Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}