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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05fe46b4eead330a23f9bfd09d8afb93ea11318ee8e52d5647acb7c45168b3ed' 
  AND token = '1vuhCfnV4eC5bsPmN5nPgOEjVMFvcRF47TVp26IfY38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}