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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a302680e23ca48d96381eeb0234076f00f401a6b69f74b71fe5f2d790b885a5' 
  AND token = 'AyoTf1B/dOnXx+abKgePQKwo35uy97a74CfJwMo55+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}