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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fc09d067b6435a8a5f72bdca0fc2c7cbf6cbc6122126cd269f4f55154384b30' 
  AND token = 'fnw0CBXYIqUmtEA4D2ty1Lza836c0Ki8pTsfrLbFAWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}