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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e22884a1a5ae48db33e52f4f286ec2765c9c3c401a5ed7da3f260d5add3eaf' 
  AND token = 'BdlieXeuVlaeXv+Ce69acDA1Lbf6Y50f90eKkqZSOnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}