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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '312b9b842991bdd1ec157703cb1b32b861e92bab8fa436d83cd7ec53d0ac7d49' 
  AND token = 'pZeHEt3CTVgZ3QMKzoP7jfQLCDxVM0E3lfnR8ravX9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}