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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '283e7c2efcff6441cf2c965da742b48eb8e1f7814e052576194220a0939b69c4' 
  AND token = 'pxgrQlZXD1QgMIHo8RtMlOOdRN9atGqYgqKg18mX3aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}