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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '979496e18aac765af648fb985d0b7eca7f281e96734e425dcdeb01d08d319532' 
  AND token = 'ZS5IblJZR7ZPZyjRHyBKOr2XHO0kFW3jKO9/2HM2Llw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}