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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5beb780191430bf7598609a37a77e7d630b9755fc0025e6b3bc9eced08ea3d8' 
  AND token = 'CEjHH0qsBPJOR3gZZCpaVgy6Zm6EHPOTsPJVwwUo29Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}