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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d2cae69c39b573d33d68901af0b4d789ea5baa91422e8d85435c9e7326ce11' 
  AND token = 'TEPD2cc4bRz7DiI5TRLJooffVFUucPzXji4qAk5/dgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}